在经历了种种波折和磨难之后,星际宝贝史迪奇(克里斯·桑德斯 Chris Sanders 配音)总算取得了“地球常住客”的身份,成为了莉洛(达科塔·范宁 Dakota Fanning 配音)家庭中的一份子。一年一度的草裙舞大赛即将拉开序幕,莉洛的妈妈曾经在比赛中夺得头筹,莉洛想要参加这届比赛,再现妈妈的风采。 就在莉洛为了参加比赛努力训练之时,史迪奇的身体开始出现一些奇怪的征兆,这些征兆从小小的麻烦演变成为了大大的混乱,再发展下去,甚至有可能威胁到史迪奇的生命安全!为了保护心爱的家人,莉洛决定去寻找发明了史迪奇的博士贾巴(大卫·奥根·斯提尔斯 David Ogden Stiers 配音),这位聪敏智慧的博士能否解决史迪奇身上的麻烦呢?Taking place between the original "Lilo and Stitch" and "Stitch: The Movie", "Lilo and Stitch 2" finds the rowdy extraterrestrial getting used to life with his new ohana. However, a malfunction in the ultimate creation of Dr. Jumba soon emerges, which reinstates his destructive programming and threatens to both ruin his friendship with Lilo and to short him out for good!