当HYDRA的秘密不再是秘密之后,该剧便可以全力在这方面展开剧情了。在第二季中,新任神盾局局长Coulson和他的团队成了「通缉犯」,HYDRA组织仍在追杀他们,而且能够调动的资源已经非常有限,但那不会阻止他们继续「为世界的和平与安全而战」——毕竟已知的和未知...Coulson and his team are now wanted fugitives with limited resources - but that's not stopping them from keeping the world safe from powerful and unseen threats everywhere. However, with new members they hardly know, will S.H.I.E.L.D. ever be trusted again?