一户普通美国家庭,父母双双外出,留下正处在青春期的儿子汉塞尔(迈克·维尔奇 Michael Welch 饰)照看妹妹格林特尔(莫莉·C·奎恩 Molly C. Quinn 饰)。不过这对兄妹可不是省油的灯,他们和格林特尔的男友阿什顿(安德鲁·詹姆斯·艾伦 Andrew James Allen 饰)沉浸在烟草毒品的幻想中,乐而忘返。期间阿什顿外出前往名为阿格尼丝(莱拉·弗林·博伊尔 Lara Flynn Boyle 饰)的老太太那里购买烟草,谁知却遭到非人的虐待,而这个可怕的老女人一切暴行的背后只是为了恢复青春。 阿什顿的失踪让格林特尔焦虑不已,次日她和哥哥相继找到阿格尼丝那里,却一无所获,但恐怖的故事并未就此中止……The pothead Ashton Crawford and his girlfriend Gretel are smoking in her room special marijuana called Black Forest supplied by the drug dealer Manny and produced by an old lady named Agnes that lives in Pasadena. Gretel's brother Hansel arrives home and Gretel tells that she will bake gingerbread cookie while Ashton will go directly to Agnes to buy more Black Forest. However Agnes is a witch and captures Ash to eat his flesh and drain his youth to maintain youth. Gretel seeks her boyfriend out and suspects of Agnes, but the police officers Ritter and Hart do not give credit to her words since Ritter knows that Ash is a pothead. Meanwhile the gang that supplies weed to Manny learns that he is selling Black Forest to his costumers and they threaten him and their leader Jorge sends a message to Agnes through Manny. However, the drug dealer is turned into a zombie by Agnes and Jorge and his gang pay a visit to her and are also turned into zombies. Soon Gretel and Manny's girlfriend Bianca decide to break into Agnes' house and they learn that she is a powerful witch. Meanwhile Hansel goes to Agnes's house to look for his sister.