在游戏机厅做着兼职“小丑”的郑开司(李易峰 饰),幼时父亲突然失踪,母亲重病住院,使得郑开司的生活非常拮据。发小“大虾米”(曹炳琨 饰)借口买房骗下了郑开司父亲留下的房产,还给他带来了巨额的欠债。神秘人物(迈克尔·道格拉斯 Michael Douglas 饰)出现,告诉郑开司,只要参加“命运号”游轮上的神秘游戏,就有机会偿还完所有欠款,一无所有的郑开司为了给青梅竹马的护士刘青(周冬雨 饰)和母亲更好的生活,只得登上游轮,开始了生存游戏,一场以“剪刀、石头、布”展开的生死较量即将登场……Muddling along without any aim, the hero Zheng Kaisi accomplishes nothing and is in debt of several millions because of borrowing money from friends. In order to pay the debt, he boards a ship called "Destiny" to attend a mysterious gambling party at the instigation of someone. Once he wins, his debts can be canceled.The game rule seems very simple. Participants shall take pokers marked with "rock, paper, and scissors" as props for seizing the star sign of the opponent. However, in the face of a group of desperate gamblers, any little flaw can be utilized in the game.