Plot Summary:Janeane Garofalo plays Dr. Abby Barnes, the "Truth About Cats and Dogs" radio question-and-answer show host who unwittingly entices a listener over the radio with her soothing voice and personality. This listener, Brian, tries to meet the Abby from the radio, but Noelle, played by Uma Thurman, is mistaken for the real thing when Brian comes to the studio. Instead of clearing things up right away, the self-conscious Abby allows her best friend, Noelle, a tall, stunning blonde, to take her place for a while. Abby takes on the made-up persona of Donna, while thinking Brian would never go for her, a short, cute, brunette, who thinks she's unattractive. As the real Abby woos Brian over the phone and radio, Noelle, the pseudo-Abby, takes her place in the flesh. As time goes on, Abby feels more and more confident that Brian would rather have the beautiful Noelle than the simply attractive Abby.
女主角是个兽医,同时又在电台主持节目,专门解决听众的宠物问题。一天男主角Calling去问一些有关他的宠物狗的问题,女主角的应对让男主角为她倾倒,但是自卑的女主角却拜托她那性感美丽的邻居代替她,从此发生一连串事件,最后有情人终成眷属,片中大丹狗对人撒娇的模样令人绝倒。