主人公一家人搬进了一间拥有160个房间的大房子,帮Winchester家看护这间房屋。但是当一股邪恶力量诱拐了他们的女儿时,他们这才明白为什么这幢房屋会赢得“美国最凶的地方之一”的“美誉”。A family moves in to look after the Winchester mansion for a few months, and soon find themselves terrorized by vengeful spirits. With the help of a paranormal investigator they'll unravel the mystery of the house.