故事发生在1991年的加州Oakland市,毒贩子Charle Cosby写了一封信给毒品教母Griselda Blanco,从此人生发生剧变。6个月后,Charles Cosby成为Blanco的情人,掌控着四千万美元的毒品生意。Blanco素有”黑寡妇“的称号,因为她会无情地处理掉她失去兴趣的男人,现在,她想要不择手段地保证Charles对她的忠诚。Charles 也渐渐感到了危机。Set in 1991 on the inner-city streets of Oakland, California, cocaine dealer Charles Cosby has his life changed forever when he writes a fan letter to the "Cocaine Godmother" Griselda Blanco, who is serving time at a nearby federal prison. Six months later, Cosby is a multi-millionaire, Blanco's lover, and the head of her $40 million a year cocaine business. Also known as "The Black Widow" for her propensity to permanently dispose of her men when she's done with them, Blanco will stop at nothing to ensure that Charles is faithful to her. Cosby soon learns that he's in way over his head.