兽医郝运(陈赫 饰)因为一场猫咪配种事故,意外发现这个世界上有转化者存在。动物管理局带走郝运,但用各种办法都无法洗掉他的记忆,只好迫使他加入动物管理局。从此郝运和战斗力超强的吴爱爱(王子文 饰)组成搭档,开始处理一桩桩动物案件......开启了一个巨大而神秘的都市精灵世界的故事。Hao Yun, a vet at a private clinic, leads a mundane life until he accidentally discovers the world is inhabited by monsters. Worried about the secret of their existence leaking, monsters capture Hao Yun and attempt to erase his memories. When their attempts fail, Hao Yun is forced to join Monsters Bureau, where he solves cases involving monsters with the help of his new partner, Wu Aiai. As Hao Yun dives deeper into this new world, he learns that even monsters must deal with the mundane struggles of everyday life and the entanglements created by human emotion.