名嘴尼尔·帕特里克·哈里斯与大家每周共度1小时的美好时光,在这一小时里,各种噱头、恶搞、幽默、观众互动、音乐、有奖问答等等,想要神马有神马,给人无限惊喜。看这劲头,哈里斯是要开创一档前无古人的超级综艺。Place a multi-threat performer, a variety show, a game show and a talk show into a blender, turn it on, and the resulting mixture is "Best Time Ever with Neil Patrick Harris". With the help of a different celebrity announcer every week, his regular stable of sidekicks and other celebrity friends, NPH kvetches with, plays games with and pranks studio audience members, at home viewers, and even unsuspecting people going about their regular business who have no idea that they will be on the show. He challenges his several celebrity friends to races and games, often of an extreme nature. And each show ends with a production number appropriately called the end of the show show.